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The UDENYCA^® on-body injector

On-the-go treatment
injected in just 5 minutes*

Please refer to the Instructions for Use before receiving UDENYCA.

Watch a video to learn about receiving treatment
with the UDENYCA on-body injector

For complete administration instructions, refer to the Instructions for Use.

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A quick guide to the UDENYCA on-body injector

The day you receive chemo, your on-body injector will be applied by your healthcare provider

The day after chemo, your dose of UDENYCA will automatically be delivered, about 27 hours after application

AFTER YOUR PROVIDER APPLIES THE UDENYCA ON-BODY INJECTOR

Your healthcare provider will walk you through what to expect while wearing the device. This quick guide can help you understand what to expect while wearing the on-body injector, but it does not replace the Instructions for Use. Please refer to them while wearing the on-body injector. Talk to your healthcare provider or pharmacist if you have any questions.

MONITOR YOUR ON-BODY INJECTOR

For the next 27 hours, occasionally check the status light for at least 10 seconds. Confirm it’s flashing green. If applied on the back of your arm, a caregiver must be available to check.

OBSERVE THE INJECTION

Before your injection begins, the on-body injector needle will automatically insert into your skin. During the injection, the on-body injector will flash a fast, green light and you may hear the pump working. It will take just 5 minutes for your dose of UDENYCA to be delivered.

CONFIRM INJECTION IS COMPLETE

When the injection is complete, a long beep will sound, and the status light will turn solid green. Confirm your injection is complete by checking to see that the status light is solid green or has switched off.

ENSURE YOUR ON-BODY INJECTOR IS EMPTY

Do not grasp the on-body injector itself to try and pull it off of your body. Instead, grab the edge of the adhesive and slowly peel the device off. Check to see if your on-body injector is empty. You should see a black line next to the empty indicator.

WHEN TO CALL YOUR HEALTHCARE PROVIDER

If your on-body injector leaked during the 5-minute injection time (adhesive may be noticeably wet or fluid is dripping from injector)

A caregiver must be available to check for leaks if the on-body injector was placed on the back of your arm

If the status light is red and the on-body injector is beeping, it is not working properly

If at any time before your dose of UDENYCA is complete, the on-body injector comes away from your skin

If the fill indicator doesn’t show as empty after your injection is complete

The UDENYCA on-body injector may be right if you:

Don’t want to return for a next-day office visit

Prefer your healthcare provider set up your treatment

Live far away from your doctor’s office or depend on a caregiver for a ride

Have a weakened immune system and need to limit exposure to infection at the doctor’s office

Looking for an in-office option that’s administered by your care team?

Consider the UDENYCA prefilled syringe

Want to self-administer treatment from the comfort of your home?

Consider the UDENYCA autoinjector

Looking for an in-office option that’s administered by your care team?

Consider the UDENYCA prefilled syringe

Want to self-administer treatment from the comfort of your home?

Consider the UDENYCA autoinjector

You’re not
in this alone

UDENYCA Solutions™, part of the Coherus Solutions™ family of patient support services, offers comprehensive support for patients who have been prescribed UDENYCA.

Learn more about support

UDENYCA is a prescription medicine used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer medicines (chemotherapy) that can cause fever and low blood cell count.

Do not take UDENYCA if you have had a serious allergic reaction to pegfilgrastim or filgrastim products.

What are possible side effects of UDENYCA?

UDENYCA may cause serious side effects, including:

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Spleen rupture: Your spleen may become enlarged and can rupture. A ruptured spleen can cause death. Call your healthcare provider right away if you have pain in the left upper stomach area or your left shoulder.
A serious lung problem called Acute Respiratory Distress Syndrome (ARDS): Call your healthcare provider or get emergency care right away if you have shortness of breath with or without a fever, trouble breathing, or a fast rate of breathing.
Serious allergic reactions: UDENYCA can cause serious allergic reactions. These reactions can cause a rash over your whole body, shortness of breath, wheezing, dizziness, swelling around your mouth or eyes, fast heart rate, and sweating. If you have any of these symptoms, stop using UDENYCA and call your healthcare provider or get emergency medical help right away.
Sickle cell crises: You may have a serious sickle cell crisis if you have a sickle cell disorder and receive UDENYCA. Serious sickle cell crises have happened in people with sickle cell disorders receiving pegfilgrastim that has sometimes led to death. Call your healthcare provider right away if you have symptoms of sickle cell crisis such as pain or difficulty breathing.
Kidney injury (glomerulonephritis): UDENYCA can cause kidney injury. Call your healthcare provider right away if you develop any of the following symptoms:
- Swelling of your face or ankles
- Blood in your urine or dark colored urine
- You urinate less than usual
Increased white blood cell count (leukocytosis): Your healthcare provider will check your blood during treatment with UDENYCA.
Decreased platelet count (thrombocytopenia): Your healthcare provider will check your blood during treatment with UDENYCA. Tell your healthcare provider if you have unusual bleeding or bruising during treatment with UDENYCA. This could be a sign of decreased platelet counts, which may reduce the ability of your blood to clot.
Capillary Leak Syndrome: UDENYCA can cause fluid to leak from blood vessels into your body’s tissues. This condition is called “Capillary Leak Syndrome” (CLS). CLS can quickly cause you to have symptoms that may become life-threatening. Get emergency medical help right away if you develop any of the following symptoms:
- Swelling or puffiness and are urinating less than usual
- Trouble breathing
- Swelling of your stomach-area (abdomen) and feeling of fullness
- Dizziness or feeling faint
- A general feeling of tiredness
Myelodysplastic syndrome and acute myeloid leukemia: If you have breast cancer or lung cancer, when UDENYCA is used with chemotherapy and radiation therapy, or with radiation therapy alone, you may have an increased risk of developing a precancerous blood condition called myelodysplastic syndrome (MDS) or a blood cancer called acute myeloid leukemia (AML). Symptoms of MDS and AML may include tiredness, fever, and easy bruising or bleeding. Call your healthcare provider if you develop these symptoms during treatment with UDENYCA.
Inflammation of the aorta (aortitis): Inflammation of the aorta (the large blood vessel that transports blood from the heart to the body) has been reported in patients who received pegfilgrastim. Symptoms may include fever, abdominal pain, feeling tired, and back pain. Call your healthcare provider if you experience these symptoms.
Bone Imaging (Nuclear Imaging): The formation of certain blood cells may increase and can be associated with short term changes in bone imaging. Your doctor should consider this when interpreting bone imaging results.
Allergies to Acrylics (UDENYCA ONBODY only): The on-body injector (OBI) for UDENYCA uses acrylic adhesive. If you have had reactions to acrylic adhesives, use of this product may result in a significant reaction.

The most common side effects of UDENYCA are pain in the bones, arms, and legs.

These are not all the possible side effects of UDENYCA. Call your healthcare provider for medical advice about side effects. To report SUSPECTED ADVERSE REACTIONS, contact Coherus BioSciences at 1-800-4-UDENYCA (1-800-483-3692) or notify the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please read the Patient Information and the Prescribing Information for UDENYCA.

Coherus Solutions, UDENYCA Solutions, and UDENYCA ONBODY are trademarks and UDENYCA is a registered trademark of Coherus Biosciences, Inc.